Which statement is wrong for Krebs' cycle?

Which statement is wrong for Krebs' cycle?
  1. There are three points in the cycle where NAD+ is reduced to NADH + H+
  2. There is one point in the cycle where FAD+ is reduced to FADH2
  3. During conversion of succinyl CoA to succinic acid, a molecule of GTP is synthesised
  4. The cycle starts with condensation of an acetyl group (acetyl CoA) with pyruvic acid to yield citric acid

Solution

The cycle starts with condensation of an acetyl group (acetyl CoA) with pyruvic acid to yield citric acid is incorrect, which can be corrected as Krebs' cycle starts with the condensation of acetyl group with oxaloacetic acid and water yield citric acid.
During the conversion of succinic acid fumaric acid FAD+ Is reduced to FADH2. During conversion of pyruvic acid to acetyl Co- A, isocitrate to oxalosuccinic acid and α-ketoglutaric acid to succinyl Co-ANAD+ is reduced to NADPH+ H+

Asked in: NEET 2017

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