Which of the following reasons in mainly responsible for graft rejection in transplantation of organs?
Which of the following reasons in mainly responsible for graft rejection in transplantation of organs?
Inability of recipient to differentiate between 'self and 'non-self' tissues/cells
Humoral immune response only
Auto-immune response
Cell-mediated response
Solution
During organ transplantation, the graft rejection takes place due to cell mediated response, in which T-cell controls the identification of Self from Non-self.
This rejection can be prevented by Immuno-suppressive agent i.e., Cyclosporin-A.