Which of the following pesticides is an acetylcho linesterase inhibitor?

Which of the following pesticides is an acetylcho linesterase inhibitor?
  1. Aldrin
  2. $\mathrm{BHC}$
  3. Endosulfan
  4. Malathion

Solution

Organophosphate (Malathion) kills insects by inhibiting enzyme cholinesterase. It is organic ester of carbonic acid. In structure, it is quite similar to acetylcholine and, therefore has strong affinity for the enzyme acetylcholinesterase, and inhibits its activity.

Asked in: NEET 2008 (Mains)

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