Which of the following immunoglobulins does constitute the largest percentage in human milk?

Which of the following immunoglobulins does constitute the largest percentage in human milk?
  1. IgM
  2. IgA
  3. IgG
  4. IgD

Solution

IgG: Smallest antibody. Only antibody that move through placenta and provide passive immunity in foetus. It occurs in form of monomer.
IgA: Only antibody that move through colostrum and provide passive immunity in infants. It occurs in form of dimer.
IgM: Largest antibody. It occurs in form of pentamer. Hence, a single antibody can negate the effect of 10 antigens. 
IgD: Very rare form of antibody. It occurs in form of monomer.
IgE: It is responsible for inducing allergic reactions and hypersensitivity

Asked in: NEET 2015 (Phase 2)

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