Which from following statements is NOT true for nucleic acids?
Which from following statements is NOT true for nucleic acids?
5' end of polynucleotide has free phosphate group.
Nucleic acids contain back bone formed of $-\mathrm{C}-\mathrm{O}-\mathrm{C}-$ linkage.
Polynucleotide has free -OH group at $3^{\prime}$ end.
Neighbouring nucleotides are bonded through phosphate diester linkage.
Solution
Option B is NOT true for nucleic acids.
In nucleic acids, the backbone is formed by a sugar-phosphate linkage rather than a \(-\mathrm{C}-\mathrm{O}-\mathrm{C}-\) linkage. The backbone is composed of alternating sugar and phosphate groups, connected by phosphodiester bonds. Each phosphate group links the \(3^{\prime}\) carbon atom of one sugar molecule to the \(5^{\prime}\) carbon atom of the next sugar molecule, which forms the characteristic sugar-phosphate-sugar chain of DNA and RNA.