Which from following is NOT a globular protein?
- Legumelin
- Egg albumin
- Myosin
- Insulin
Solution
Classification of proteins into globular and fibrous types depends on shape and solubility characteristics. Globular proteins exhibit spherical morphology, compact folding, and aqueous solubility, while fibrous proteins display elongated structures, mechanical functions, and water insolubility.
Evaluating the options: Legumelin serves as a storage protein with globular characteristics; egg albumin demonstrates classical globular properties with high solubility; insulin functions as a compact hormonal protein with globular conformation.
Myosin functions as the motor protein in muscle contraction, featuring an elongated fibrous tail domain that assembles into insoluble filaments. Despite possessing a globular head region, its primary classification derives from its fibrous structural role.
Thus, myosin represents the non-globular protein among the options.
Asked in: MHT CET 2025 (25 April Shift 1)