Under which of the following conditions will there be no change in the reading frame of the following mRNA?…

Under which of the following conditions will there be no change in the reading frame of the following mRNA?
5'AACAGCGGUGCUAUU 3'
  1. Insertion of G at 5th position
  2. Deletion of G from 5th position
  3. Insertion of A and G at 4th and 5th positions respectively
  4. Deletion of GGU from 7th 8th and 9th positions

Solution

Genetic codes are read in the sequence of 3. Insertion or deletion of a single base changes the reading frame of codon and is called frameshift mutation. However, insertion or deletion of three or its multiple bases insert or delete in one or multiple codon hence one or multiple amino acids and reading frame remains unaltered from that point onwards.

Asked in: NEET 2019 (All India)

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