Semiconservative replication of DNA was first demonstrated in :
Semiconservative replication of DNA was first demonstrated in :
Salmonella typhimurium
Drosophila melanogaster
Escherichia coli
Streptococcus pneumoniae
Solution
The semiconservative replication of DNA was first demonstrated by Matthew Meselson and Franklin Stahl in 1958 using Escherichia coli (E. coli) bacteria. In their experiment, they used isotopic labeling of nitrogen atoms to trace the newly synthesized DNA strands, proving that each new DNA molecule consists of one strand from the original DNA and one newly synthesized strand.