The correct answer is option (1) as:
A. Malignant tumors - Exhibit the property of metastasis
B. MALT - Mucosa Associated Lymphoid Tissue
C. NACO - National AIDS Control Organisation
D. $\alpha$-Interferons - Biological response modifiers given to cancer patients that activate their immune system and help in destroying the tumor.
Thus, correct match is, A-III, B-IV, C-II, D-I and therefore the correct answer is option (1).
The other options i.e., (2), (3) and (4) are incorrect as they represent mismatches.