Least reactive alkyl chloride in a $\mathrm{S}_{\mathrm{N}} 2$ reaction is

Least reactive alkyl chloride in a $\mathrm{S}_{\mathrm{N}} 2$ reaction is
  1. 1-Chloro butane
  2. 1-Chloro 2-Methyl propane
  3. 2-Chloro 2-Methyl propane
  4. 2-Chloro butane

Solution

An $\mathrm{S}_{\mathrm{N}} 2$ reaction involves a single-step concerted mechanism and the alkyl halide that is most substituted at the $\alpha$-position will be least reactive. Thus, 2-chloro-2-methyl propane will be least reactive.

Asked in: AP EAMCET 2023 (16 May Shift 2)

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