In the context of hereditary diseases, consider the following statements: 1. Passing on mitochondrial…

In the context of hereditary diseases, consider the following statements: 1. Passing on mitochondrial diseases from parent to child can be prevented by mitochondrial replacement therapy either before or after in vitro fertilization of egg. 2. A child inherits mitochondrial diseases entirely from mother and not from father. Which of the statements given above is/are correct?
  1. 1 only
  2. 2 only
  3. Both 1 and 2
  4. Neither 1 nor 2

Solution

Mitochondrial replacement therapy (MRT) can prevent the transmission of mitochondrial diseases (Statement 1 correct). Mitochondrial DNA is inherited entirely from the mother since the sperm's mitochondria are usually destroyed after fertilization (Statement 2 correct).

Asked in: UPSC Prelims 2021

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