In an amino acid, the carboxylic group ionises at $\mathrm{pH}=2.56\left(\mathrm{pK}_{\mathrm{a}_1}\right)$…

In an amino acid, the carboxylic group ionises at $\mathrm{pH}=2.56\left(\mathrm{pK}_{\mathrm{a}_1}\right)$ and ammonium ion ionises at $\mathrm{pH}=9.38\left(\mathrm{pK}_{\mathrm{a}_2}\right)$. The isoelectric point of the amino acid is at
  1. 11.94
  2. 6.82
  3. 5.97
  4. 3.41

Solution

$\mathrm{p} K_{a 1}=256, \mathrm{p} K_{a_2}=9.38$ At isoelectric point $ (\mathrm{pH})=\frac{\mathrm{p} K_{a_1}+\mathrm{p} K_{a_2}}{2}=\frac{2.56+9.38}{2}=5.97 $

Asked in: AP EAMCET 2021 (24 Aug Shift 1)

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