Identify the correct statement on 'inhibin':

Identify the correct statement on 'inhibin':
  1. Inhibin is a protein secreted by granulosa in female
  2. Inhibin secreted in response to FSH, and its major action is the negative feedback control of pituitary FSH secretion
  3. Inhibin is a protein secreted by Sertoli in female
  4. Inhibin inhibits the secretion of GnRH from the hypothalamus

Solution

Inhibin is a protein secreted by granulosa (female) and Sertoli (male) cells in response to FSH, and its major action is the negative feedback control of pituitary FSH secretion. It is found in blood plasma, although difficult to detect until recently. Inhibin is produced in the gonads, pituitary gland, placenta, corpus luteum and other organs. Inhibin does not inhibit the secretion of GnRH from the hypothalamus

Asked in: NEET 2016 (Phase 1)

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