How many times decarboxylation occurs during each TCA cycle?

How many times decarboxylation occurs during each TCA cycle?
  1. Once
  2. Twice
  3. Thrice
  4. Many

Solution

During TCA cycle, first decarboxylation occurs when Oxalosuccinic acid is converted into $\alpha$-ketoglutaric acid and second decarboxylation occurs when $\alpha$-ketoglutaric acid is converted into succinyl CoA.

Asked in: NEET 2023 (Manipur)

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