Given below are two statements : one is labelled as Assertion (A) and the other is labelled as Reason (R).…

Given below are two statements : one is labelled as Assertion (A) and the other is labelled as Reason (R). Assertion (A) : FSH which interacts with membrane bound receptors does not enter the target cell. Reason (R) : Binding of FSH to its receptors generates second messenger (cyclic AMP) for its biochemical and physiological responses. In the light of the above statements, choose the most appropriate answer from the options given below;
  1. Both (A) and (R) are correct and (R) is the correct explanation of (A)
  2. Both (A) and (R) are correct but (R) is not the correct explanation of $(\mathrm{A})$
  3. (A) is correct but (R) is not correct
  4. (A) is not correct but (R) is correct

Solution

Because FSH (Follicle Stimulating Hormone) is a fat soluble hormone, it cannot cross the plasma membrane for entering into target cell, but generate secondary messenger (cAMP) which in turn regulate cellular metabolism.

Asked in: NEET 2022 (Phase 2)

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