Consider the following statements: ( A ) Coenzyme or metal ion that is tightly bound to enzyme protein is…

1. Both $\left(\mathrm{A}\right)$ and $\left(\mathrm{B}\right)$ are correct.
2. $\left(\mathrm{A}\right)$ is true but $\left(\mathrm{B}\right)$ is false.
3. Both $\left(\mathrm{A}\right)$ and $\left(\mathrm{B}\right)$ are false.
4. $\left(\mathrm{A}\right)$ is false but $\left(\mathrm{B}\right)$ is true

Solution

Many enzymes show catalytic activity only in association with certain non-protein substances. Those substances are known as cofactors (cofactors may be simple metal ions, e.g. Mg⁺⁺ or K⁺ etc.). The enzymes which works only in presence of cofactors are called  apoenzymes. An organic non-protein cofactor which is easily separable from the apoenzyme is called coenzyme, and the non-protein organic cofactor that is tightly bound to and non-dissociable from the enzyme is termed as prosthetic group, e.g. biotin of carboxylases, haem of hemoglobin, etc.

Asked in: NEET 2019 (All India)

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