A strong base an abstract an $\alpha$-hydrogen from

A strong base an abstract an $\alpha$-hydrogen from
  1. Alkane
  2. Alkene
  3. Amine
  4. Ketone

Solution

Since the carbonyl carbon is electron deficient, so most susceptible to attack by nucleophilic reagents or base. A base increases the acidity of hydrogen atom attached to the \(\alpha-C\) of the ketones or aldehydes. That- why \(\alpha\)-hydrogen is easily abstracted from ketones by a base, e.g. in aldol condensation reaction, \(\alpha\)-hydrogen atom of aldehyde or ketone is abstracted by a strong base.

Asked in: NEET 2008 (Mains)

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